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February 1, 2008 Esprit Health Announces Major Upgrade to eSphere
September 5, 2007 National Institute of Environmental Health Science Selects Esprit Health - Signs Institute-Wide Agreement
August 18, 2007 NIAMS To Utilize Esprit Health’s eSphere for Rheumatology Fellowship Program
August 17, 2007 NCI Center for Cancer Research Selects Esprit Health’s eSphere Online for Nursing Genetics and Genomics Survey
August 1, 2007 Esprit Health Expands Healthcare Interoperability through new HL7 products
January 7, 2007 NIH Clinical Center Adopts Esprit Health’s eSphere to provide informatics support for Bereavement Program
 
July 5, 2006 Esprit Health announces Version 2 of eSphere Biospecimen Banking System
June 11, 2006 NIDDK Picks Esprit Health’s eSphere for Sleep Study Data Management
December 5, 2005 Esprit Health Signs Agreement with University of Chicago
November 11, 2005 Esprit Health Chosen Again by National Human Genome Research Institute
October 3, 2005 NIH Physical Disabilities Branch to use Esprit for Protocol Management
September 12, 2005 NIH Pain and Palliative Care Service picks Esprit for Clinical Management
July 2, 2005 University of Miami Picks Esprit Health's eSphere
June 13, 2005 East Jefferson General Hospital Selects Esprit Health for Clinical Transformation
March 4, 2005 Esprit Health Announces Major eSphere Release (Version 4.0)
January 31, 2005 NIMH Selects eSphere for Data Management
November 12, 2004 Esprit Health Announces Availability of new eSphere Specimen Tracking module
August 31, 2004 NHGRI Picks Esprit Health's eSphere for Internet based survey to family physicians
July 2, 2004 Esprit Health Releases White Papers on Business and Clinical Transformation
June 15, 2004 NIEHS To Utilize Esprit for Myositis Study
May 1, 2004 Esprit Health Discusses Solutions for Patient Logistics at 17th Annual IEEE Meeting
April 15, 2004 Esprit Health Presents Data in Context Approach at BECON/BISTIC Symposium
April 3, 2003 NIH Clinical Center and Esprit sign consulting agreement
November 30, 2002 NIEHS Picks Esprit Health's eSphere for Data Management
September 30, 2001 Esprit Health, SRA Int'l Partner to Deliver Integrated Clinical Trial Solutions
July 23, 2001 Esprit Health Discusses Protocol Centric Approach at IEEE Meeting
May 5, 2001

Esprit Health and National Institutes of Health Sign Major Renewal Contract for Protocol Mapping

April 7, 2001 Esprit Health Introduces New eSphere Release
November 1, 2000 Esprit Health unveils new Customer Care web site
September 4, 2000 Esprit Health Announce Release of eSphere Version 1.3
April, 30, 2000 Esprit Health and National Institutes of Health sign agreement to expand use of eSphere
September 3, 1999 Jackson Memorial Hospital picks Esprit Health’s eSphere
June 1, 1999 Esprit Health Announce Web Site
January 25, 1999 Esprit Health Signs Agreement with National Institutes of Health



Esprit Health Announces Major Upgrade to eSphere

CHICAGO, ILL., February 1, 2008 Esprit Health, LLC developer of technology for automating the clinical research data management process, BioSpecimen management Systems, Case and Disease Management Systems and clinical / physician decision support systems announced a major release of eSphere, its integrated product platform.

“The latest major release of eSphere, Version 5, includes a number of significant technical enhancements and improvements which enables Esprit Health to maintain its leading position as a state-of-the-art informatics solution for both its current and future customers” said Frank Pierce, President and CEO of Esprit Health. Included in Version 5 is:

·         Support for Windows Vista. eSphere 5.0 has been fully tested for Vista compatibility including Windows Vista theme support

·         Support for 64-bit CPU architecture. eSphere 5.0 will operate on 64-bit (e.g. Intel Itanium) servers taking advantage of the scalable performance, reliability, and headroom for the most computer-intensive workloads to quickly meet mission-critical needs.

·         Web Services. eSphere 5.0 Web services architecture enables e-business services to be described, published, discovered, and invoked dynamically in a distributed computing environment. Future upcoming releases of eSphere On-Line, the web-based version of eSphere will take full advantage of this capability.

·         Support for “dual core” or multi-processor computers. eSphere 5.0 will automatically use multiple cores when available. Overall performance can be expected to improve.

·         HL7 Interface Support. eSphere 5.0 has a full complement of bi-directional HL7 interfaces that allows data to be seamlessly shared between eSphere and other systems. Interfaces include: ADT, Orders, Results, Lab Query and Retrieve, and Medications.

In addition to these major technical enhancements, Version 5.0 features an unprecedented number of valuable enhancements and system improvements. Version 5 contains more than 200 new features and enhancements -- from a myriad of major system operating improvements to several completely new modules.

About Esprit Health

In addition to these major technical enhancements, Version 5.0 features an unprecedented number of valuable enhancements and system improvements. Version 5 contains more than 200 new features and enhancements -- from a myriad of major system operating improvements to several completely new modules.

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

National Institute of Environmental Health Science Selects Esprit Health -
Signs Institute-Wide Agreement

CHICAGO, ILL., September 5, 2007 Esprit Health, LLC a privately held company that provides technology for automating 100% of the clinical documentation and research process, announced today that it has signed an agreement with the National Institute of Environmental Health Science (NIEHS), Research Triangle Park, NC, to provide eSphere, for all of the informatics support for Institute.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical research data management. It is a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

The eSphere system from Esprit Health is the most advanced clinical research support systems in the industry. In addition, at the NIEHS the system will automate everyday clinical tasks such as appointment scheduling, physician and nursing documentation of clinical interventions, prescribing and documenting medication administration. Although NIEHS is implementing eSphere principally for its new Clinical Research Unit (CRU) facility, eSphere will enable physicians, researchers and support staff to have access to key clinical information on each patient including the medication history, problem list, allergies, clinic notes, etc.

eSphere will allow NIEHS researchers to access both clinical and research information anywhere at anytime and provide robust tools for analysis. Additionally, eSphere includes HL7 interfaces to other systems, and a wide range of medical devices. And the eSphere BioSpecimen Management™ System enables the NIEHS to collect, process, catalog, storage, query and retrieve annotated BioSpecimens. The eSphere BioSpecimen Management System is a comprehensive system that is specifically developed for both individual researchers, and large research groups that manage BioSpecimen repositories. Implementation of the eSphere system is scheduled to begin in Fall, 2007.

“We are extremely proud that NIEHS, one of the most prestigious Institutes in the NIH, selected eSphere as their electronic health information partner,” said Frank Pierce, Chief Executive Officer of Esprit Health. “This technology, through the real-time information and connectivity it provides, allows researchers to focus on subjects and the related research, not paperwork, and deliver a seamless, high quality subject and research experience.”

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

NIAMS To Utilize Esprit Health’s eSphere
for Rheumatology Fellowship Training Program

CHICAGO, ILL., August 18, 2007 Esprit Health, LLC a privately held company that provides technology for automating 100% of the clinical research process, announced today that it has signed an agreement with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) ), Bethesda MD, to provide eSphere, for informatics support for the Rheumatology Fellowship Training Program.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical research data management. It is a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

“We are very proud to have been selected as the solution for the NIAMS’s Rheumatology Fellowship Program” noted Frank Pierce, CEO and President of Esprit Health. “By selecting eSphere for this program NIAMS will be providing the ultimate tool to capture, access and report information that will help analyze their data, streamline processes, better understand program performance and costs and ultimately produce better outcomes.”

eSphere provides the NIAMS Rheumatology Fellowship Program with an effective way to manage the graduate medical education program. eSphere specifically addresses all of the data collection and data management problems faced by the program. Specifically, the system provides (1) a resident information database, (2) credential tracking, (3) Web-based timesheet, and (4) accurate reporting and billing computations based on actual time, (5) patient/clinic scheduling, (6)diagnosis tracking, (7) procedure tracking, (8)evaluation management and reporting.

“Within two weeks the system was installed and operational and utilized by all of our fellows,” said Dr. Mark Gourley, Director for Clinical Care and Training at NIAMS. “To be able to generated program reports so quickly went well beyond our expectations. We are already realizing the benefits from eSphere.”

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

NCI Center for Cancer Research Selects Esprit Health’s eSphere Online
for Nursing Genetics and Genomics Survey

CHICAGO, ILL., August 17, 2007 Esprit Health, LLC a privately held company that specializes in technology for automating the clinical research process, announced today that it has signed an agreement with the Genetics Branch of the Center for Cancer Research of the National Cancer Institute NCI), Bethesda MD, to provide eSphere Online, an Internet based data capture tool and complete clinical research data management system.

“We are very excited to work with Kathleen Calzone, the Principal Investigator, on this very important project” noted Frank Pierce, CEO and President of Esprit Health.

In this initial project, a web-based survey will be pilot tested with National Cancer Institute (NCI) and NIH Clinical Center (CC) nurses to assess attitudes, practices, receptivity, confidence and competency of the nursing workforce integrating genetic and genomics information related to common multi-factorial diseases in preparation for a national nursing workforce survey.

Genetic and genomic science is redefining the understanding of the continuum of human health and illness. Therefore, recognition of genetics and genomics as a central science for health professional knowledge is essential. Because all diseases and conditions have a genetic or genomic component, options for care for all persons will increasingly include genetic and genomic information along the pathways of prevention, screening, diagnostics, prognostics, selection of treatment, and monitoring of treatment effectiveness. The clinical application of genetic and genomic knowledge has major implications for the entire nursing profession regardless of academic preparation, role or practice setting. Healthcare will increasingly demand that the registered nurse (RN) use genetic and genomic information and technology when providing care. These expectations have direct implications for RN preparatory curricula, as well as for the 2.9 million practicing nurses.

“By selecting eSphere Online for their Internet based survey of nurses, the Center for Cancer Research will be able to quickly collect and then analyze their survey data, and ultimately decide on whether or not to proceed with their national nursing survey,” said Pierce.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical study management is now integrated with eSphere Online a web-based tool for data collection. Together they form a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

Esprit Health Expands Healthcare Interoperability through new HL7 products

Four new interface software releases to eSphere system advance the
Efficiency, Accuracy and Security of Shared Clinical Data


CHICAGO, ILL., August 1, 2007 Esprit Health, LLC developer of technology for automating the clinical research data management process, announced the release of four new integrated enhancements to eSphere, its Clinical Information System.

The eSphere System has been expanded with a full complement of bi-directional HL7 interfaces that allows data to be shared between eSphere and other systems that is virtually seamless. Adding to the HL7 ADT interface previously available to its clients, the new interfaces include:

• Orders: receipt of orders from any HIS including cancellations
• Medications: receipt of medications from any HIS including order completion
• Labs: receipt of lab results from any LIS or HIS, including query and retrieval capability
• Results : sending results from eSphere to any HIS

Through these HL7 interfaces, data from the HIS can be sent to eSphere and data from the eSphere system can be sent directly to the client’s hospital data repository. This eliminates the necessity of scanning or printing eSphere records and attaching it to the patient chart. A real-time flow of patient demographics, ordering, and results information is now benefiting all Esprit Health clients.

In addition to the completion of the full complement of HL7 interfaces, Esprit Health has provided advanced tools to system operators that enable continuous monitoring of all interfaces, review of HL7 message content and full audit trail functionality.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical study management is now integrated with eSphere Online a web-based tool for data collection. Together they form a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

NIH Clinical Center Adopts Esprit Health’s eSphere to provide
informatics support for Bereavement Program

CHICAGO, ILL., January 16, 2007 Esprit Health, LLC a privately held company that specializes in technology for automating the clinical research process, announced today that it has signed an agreement with the National Institute of Health Clinical Center, Bethesda MD, to utilize eSphere , a complete clinical research data management system for the Clinical Center’s Bereavement Program.

Patients and their families often describe CC physicians and nurses as honorary members of the family. And when a patient dies—either while at the Clinical Center or after leaving treatment—those relationships between CC staff and patients’ families do not end, or at least they shouldn’t, according to the CC Pain and Palliative Care Service (PPCS) team. “Families deserve that connection,” says Dr. Ann Berger, PPCS chief. “That emotional need is not over for the family the day the patient dies—and it shouldn’t be for us either.” As a means of continuing that service and support for families and staff, PPCS recently implemented a bereavement program. “Bereavement is part of palliative care’s mission,” she says.

Since its inception five years ago, PPCS has worked with resources all over the Clinical Center, from social workers and volunteers to therapists with the recreation department—to improve the quality of life for CC patients. After noting the increasing need for a formal bereavement program, Berger adopted the cause as one of her team’s top priorities.

When a patient dies, a physician, nurse or social worker notifies the bereavement program liaison. The liaison then consults with the patient’s attending physician to determine whether the family would respond well to bereavement support. Once the family is placed in the program, a volunteer arranges for a card to be signed by everyone who cared for the patient and sends it to the family. At one month, six months, one year and 13 months after the death, families receive a phone call from a volunteer. If there seems to be a risk of complicated grief, the volunteer will try to help the family member find a bereavement support group in the local community.

eSphere, provides the PPCS with innovative methodology to track bereavement families, develop a customized follow-up program, provide periodic reminders to program staff and volunteers on who to call and when and monitor the overall program. With a workflow process designed collaboratively by Esprit health and the PPCS, eSphere will help monitor every step in the process and provide management with statistical reports on the program’s effectiveness.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

Esprit Health Announces Version 2 of eSphere Biospecimen Banking System

CHICAGO, ILL., July 30, 2006 Esprit Health, LLC a privately held company that specializes in technology for automating the clinical research process, announced today announced today that it has released Version 2 of the eSphere, Biospecimen Banking System

The eSphere Biospecimen Banking System is a comprehensive system for the collection and archiving of human biospecimens for research. According to Frank Pierce, President of Esprit Health, “Use of the eSphere system enables our clients to collect biospecimens and associated clinical data for molecular-based clinical trials and to enter biomedical research collaborations in which our clients will conduct prospective biospecimen collections for researchers across the country. Adoption of the eSphere system will also enable clients to participate in the growing network of medical institutions across the country that are collecting and sharing high quality biospecimens and clinical data in support of the advancement of molecular medicine.”

“The adoption of this system positions our client institutions squarely in the emerging field of molecular medicine, where diagnosis and treatment are based on disease origin and progression at the molecular level. This system provides the IT and logistical infrastructure to support the growing number of molecular-based clinical trials, while ensuring full privacy and confidentiality for patient donors. We are very enthusiastic about our role in the development of a new generation of diagnostics and therapeutics based on the molecular origins of disease” said Mr. Pierce.

The eSphere Biospecimen Banking System is an integrated system for biorepository operations at one or multiple geographic sites. As the network of eSphere system users expands, resources are easily shared across organizations, while ensuring high quality biospecimens and data at all sites.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical study management is now integrated with eSphere Online a web-based tool for data collection. Together they form a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

NIDDK Picks Esprit Health’s eSphere for Sleep Study

CHICAGO, ILL., June 16, 2006 Esprit Health, LLC a privately held company that specializes in technology for automating the clinical research process, announced today that it has signed an agreement with the Clinical Endocrinology Branch of the National Institute of Diabetes and Digestive & Kidney Diseases (NIDDK), Bethesda MD, to provide eSphere, a complete clinical research data management system.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical study management. It is a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

“We are very proud to have been selected as the solution for the Clinical Endocrinology Branch’s study on chronic sleep deprivation as a risk factor for metabolic syndrome and obesity noted Frank Pierce, CEO and President of Esprit Health. “By selecting eSphere for their system, the NIDDK will be giving its Principal and Associate Investigators, Research Nurses, and Administrators access to information that will help analyze clinical trial data, increase efficiencies, better understand resource utilization and costs and ultimately produce better outcomes.”

Obesity and chronic sleep deprivation have both become increasingly pervasive medical problems in recent years. The prevalence of adult obesity has doubled over the past 30 years and continues to increase. In addition, industrial societies attach an economic value to maximizing the waking period to the longest tolerable limit by sleeping as little as possible. Average sleep time has decreased over the last century by 2 hours. Chronically sleeping less has been associated with increased weight, endocrine and metabolic health risks including glucose intolerance, cardiovascular disease, and mortality. The possibility that the current epidemic of obesity and metabolic health risks may be partially related to insufficient sleep is now being recognized. The objective of this proof-of-concept controlled trial is to investigate the impact of increasing sleep time in chronically sleep-deprived, obese subjects.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

Esprit Health Signs Agreement with the University of Chicago to Provide BioSpecimen Banking System

CHICAGO, ILL., December 5, 2005 The University of Chicago, world renowned for its research, treatment and clinical care has agreed to use Esprit Health's eSphere Clinical Data Management System for its BioSpecimen Banking System. Under the terms of the agreement, the University of Chicago's Department of Pathology will use the software to collect, store and retrieve normal and diseased samples for banking and future analysis.

The eSphere BioSpecimen Bank system will manage this repository of bio-specimens and make them available for research. It meets researchers’ needs to store samples, link and review relevant clinical data, monitor daily operations and extract data sets for research and analyses. eSphere includes the capability to model workflow processes for the procurement, cataloging inventory management and retrieval of bio-specimens and pathology data. Furthermore, the database manages the process for linking and recording consents and facilitates electronic sharing of data to support collaborative efforts of different internal departments at The University of Chicago and externally with other institutions. Esprit Health created the solution, the only technology of its kind to respond to the unique workflow and data capture needs of the biospecimen resource center.

"We are very proud to say that the University of Chicago, with the tremendous breadth and scope of its research programs has invited us to work on this important project," said said Frank Pierce , President of Esprit Health.  "We are excited about the opportunity to work with the University of Chicago to provide a BioSpecimen Banking System that sets the standard in the market.  By selecting eSphere for their system, the University of Chicago has validated eSphere as the leading technology for clinical research data management."

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

Esprit Health Chosen Again by National Human Genome Research Institute

CHICAGO, ILL., November 11, 2004Esprit Health, LLC a privately held company that specializes in technology for automating the clinical research process, announced today that it has signed a second agreement with the National Human Genome Research Institute (NHGRI), Bethesda MD, to provide eSphere, a complete clinical research data management system.

“We are very excited to continue our work with Dr. Colleen McBride, Chief of the Social and Behavioral Research Branch of the NHGRI on this very important project” noted Frank Pierce, CEO and President of Esprit Health. 

In recognition of emerging genomic innovations and their potential for improving primary care practice, the American Academy of Family Physicians (AAFP),in collaboration with the National Human Genome Research Institute (NHGRI) will be conducting a followup study on family physicians’ attitudes and practices related to the genetics of complex disorders.  The AAFP is one of the largest medical organizations with a membership that comprises a group of more than 50,000 active family physicians.  In the second phase, a web-based follow-up survey will be conducted of members of AAFP who completed the initial survey. 

“By selecting eSphere Online for their Internet based survey of AAFP physicians, the NHGRI will be able to quickly collect and then analyze their survey data, and ultimately produce better outcomes,” said Pierce.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical study management is now integrated with eSphere Online a web-based tool for data collection.  Together they form a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com. Visit Esprit at www.esprithealth.com.

NIH Physical Disabilities Branch to use Esprit for Protocol Management

CHICAGO, ILL., October 3, 2005 Esprit Health's eSphere Clinical Research Data Management System has been chosen by the NIH Physical Disabilities Branch, Bethesda. Maryland to automate protocol management for all of the protocols in the branch. Under the terms of the agreement, the Physical Disabilities Branch will use the software to integrate the five protocols currently approved as well as those planned in the future.

"The selection of eSphere by the NIH Physical Disabilities Branch adds yet another group at the NIH that has decided to use eSphere to meet the growing demands for clinical research data management," noted Frank Pierce, CEO and President of Esprit Health.  "The unparalleled success of our work at the NIH over the past seven years has established our reputation as the premier system of its kind. The secret to our success is our collaborative on-site implementation approach – implementation and consulting services that are clearly unique in the industry. Focused on achieving the maximum benefits for our customer in the most efficient timeframe, this approach provides the full rewards associated with the use of our system and a quick return on investment. This simply means that our customers can publish results sooner."

“Our services and software, available now, can help researchers with their protocol needs. At the NIH CLincial Center, getting started with this solution is easy because the database (i.e. Oracle) and server is already installed and connectivity is provided by the Clinical Center,"   said Donald Dorfman , Vice President of Esprit Health.  "All that is needed is a computer (PC or MAC) that is either on the Clinical Center network or has Internet access (or both) and the creation of a user account."

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

NIH Pain and Palliative Care Service picks Esprit for Clinical Management

CHICAGO, ILL., September 12, 2005 Esprit Health, LLC a privately held company that specializes in technology for automating the clinical documentation processes, announced today that it has signed an agreement with the Pain and Palliative Care Service of the National Institute's of Health Clinical Research Center, Bethesda MD.to provide a clinical documentation / consult service system for use throughout the NIH.

"The eSphere system will provide the Pain and Palliative Care Service with a complete end to end system," said Frank Pierce, CEO and President of Esprit Health.  "The system is a highly flexible, extensible, user-driven system that can be used to help manage any process as well as build and maintain a database for research purposes."

Features of the system include:

·         An automated system to address the needs of the entire process: Receipt of orders for PPCS service, Initial Pain Consultation, andd follow-up re-assessments and notes.

·         Workflow system to support best practices.

·         Produce chronology of follow-up re-assessments, medications and treatment modalities

·         Comprehensive database for clinical information, including: Demographics, Pain Assessment, PPCS treatments and interventions, and other clinical data.

·         Provide data to facilitate sharing and collaborative efforts in the research community.

Upon implementation, the NIH Clinical Reasearch Center Pain and Palliative Care Service will have a comprehensive automated process for the data capture of the incoming order, for documentation of the initial Pain Consult and all follow-up visits and contacts, and for progress notes.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

University of Miami Picks Esprit Health's eSphere

CHICAGO, ILL., July 2, 2005 Esprit Health's eSphere Clinical Data Management System has been chosen as the Chronic Kidney Disease Clinic system by the Univeristy of Miami Miller School of Medicine, Miami, Florida. Under the terms of the agreement, UMMC Department of Nephrology will use the software to integrate Nephrology/Renal consults, CKD clinic visits and other Renal clinics.

"The selection of eSphere by UMMC underscores the momentum that we are now experiencing in the market," noted Frank Pierce, CEO and President of Esprit Health.  "The strategy of using best-of-breed systems is more appealing than ever to customers."

“We are very excited about the opportunity to work with the University of Miami to provide informatics to the Department of Nephrology,”    said Donald Dorfman , Vice President of Esprit Health.  "By selecting eSphere for their system, the UMMC Department of Nephrology will be giving its clinicians a set of tools that will help analyze, measure, and produce better outcomes."

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

East Jefferson General Hospital Selects Esprit Health for Clinical Transformation

CHICAGO, ILL., June 13, 2005Esprit Health, LLC a privately held company that specializes in information technology for automating processes, announced that it has agreed to provide its workflow / process management software solutions to East Jefferson General Hospital, Metairie, Louisiana.

"Esprit Health offers an extremely compelling solution for workflow documentation and clinical productivity improvement," said Frank Pierce, President of Esprit Health. "We view the release of eSphere continues to revolutionize the way informatics technology supports clinical researchers software as a strategic tool to help pur customers automate, coordinate and streamline te continuum of care."

With the addition of EJGH, Esprit Health customer base now includes organizations focusing on clinical documentation, clinical transformation, case management, disease management, clinical trials, and specimen management.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

Esprit Health Announces Major eSphere Release (Version 4.0)

CHICAGO, ILL., March 4, 2005Esprit Health, LLC a privately held company that specializes in information technology for automating the clinical research process, today announced eSphere 4.0 the latest version of its industry leading protocol-centric data management system for healthcare.

"Esprit is known for offering customer-driven improvements to our easy-to use products that deliver tremendous value," said Donald Dorfman, Vice President of Esprit Health. "The newest major release of eSphere continues to revolutionize the way informatics technology supports clinical researchers case/disease managers, and enterprise clinical transformation efforts by offering ease-of-use, performance, and breadth of capabilities, all at an affordable price."

eSphere offers a comprehensive suite of solutions that are flexble, customizable, and scalable. Version 4.0, the new release, features nearly 100 new features and enhancements ranging from system improvements to new software modules. Several noteworthy enhancements and additions include:

Expanded Management Reporting

·         Easy access to data coupled with standard reports and ad-hoc query capability provides the tools needed for in-depth data analysis and interpretation. Version 4 introduces expanded reporting in the areas of costing, volume projections and cohort analyses.

Fast Access to Your Data – eSphere Data Export

·         Quick data export: data can be instantly exported to tab delimited, comma separated values, XML and XLS (Excel), SPSS, and SAS formats too reduce the time required to generate detailed statistical analyses and share information.

Medications and IVs

·         Quick data export: data can be instantly exported to tab delimited, comma separated values, XML and XLS (Excel), SPSS, and SAS formats too reduce the time required to generate detailed statistical analyses and share information.

Graphing Capability

·         eSphere reports now have the additional capabilitiy to display graphically. Graph Reports can be set to display an intial view of tabular data, graph data (e.g. bar charts, line plots, etc) or both.

Integration with eSphere Online

·         eSphere Online facilitates the entry of data over the Internet to more efficiently collect data. eSphere Online seamlessly links with eSphere, an integrated end-to-end solution for data management. All data collected via the Internet is downloaded and stored central secure Oracle database. From eSphere a myriad of reports and data extraction tools provide the ability to conduct unlimited analyses

Form Generator

·         New to Version 4.0! - The new Form Editor brings easy drag and drop functiolaity to the process of designing eSphere forms. From data elements and content to special layout tools, the new Form Editor dramitcally speeds up the forms creaton process. information.

Pricing and Availability

eSphere 3.0 is available now. Contact Esprit Health at 312-787-6412 for pricing, as well as information on training, consulting and technical support.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

Esprit Health Announces New Specimen Tracking Module

CHICAGO, ILL., March 4, 2005Esprit Health, LLC a privately held company that specializes in information technology for automating the clinical research process, today announced the general availability of its newest addition to the suite of solutions for eSphere, its industry leading clinical research data management system for healthcare.

"For researchers and laboratories, the process for the storage and periodic retrieval of research specimens is an incredibly time consuming," said Donald Dorfman, Vice President of Esprit Health. "The collection of specimen samples in a research study as well as for future research needs release of eSphere continues to revolutionize the way informatics technology supports clinical researchers requires that they be correctly identified, cataloged, stored under proper conditions and be easily retrived when needed. The eShere Specimen Tracking module provides the ability to easily perform these functions which are critically important to research."

The Specimen Tracking System can be implemented as a standalone system to catalog specimens, track their location and retrieve them as needed or as part of eSphere, a complete research data management system. The eSphere system includes a comprehensive demographic database that can be used with as much detailed data as needed. Subject data and cohort assignments are integrated with protocol events and data as well as the specimen information.

Features of the Specimen Tracking system include:

·         Easy to setup, understand and use

·         Subject query and identification with extensive database of demographic data

·         Catalog specimen receipt manually or bar code scan

·         Automatic link of specimen and specimen type to subject

·         User defined rules assist data entry and improve accuracy

·         Automatic assignment to storage locations –floors/room and refrigerator, shelf, box and position in the box

·         Tracking of refrigerator and box capacity and automatic assignment to new box

·         Visual map of box contents with icons reflecting specimen type

·         Single repository for all samples avoids duplication of assignment location

·         Quick and accurate data entry tracks descriptors and all identification numbers

·         Audit trail maintains complete specimen history (when received, entered into system, aliquoted, and delivered).

·         Status of all specimens (e.g. quantity left, number of times retrieved, reason for retrieval) available at any time

·         Powerful search engine with customizable parameters is easy to use and produces results immediately

Pricing and Availability

eSphere SPEcimen Tracking System is available now. Contact Esprit Health at 312-787-6412 for pricing, as well as information on training, consulting and technical support.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

NIMH Selects eSphere for Data Management of Studies

CHICAGO, ILL., January 31, 2005 Esprit Health, LLC a privately held company that specializes in technology for automating the clinical research process, announced today that it has signed an agreement with the National Institute of Mental Health Science (NIMH), Bethesda MD, to provide eSphere, a complete clinical research data management system.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical study management.  It is a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

“We are excited and appreciate the opportunity to work with the Clinical Neuro-Endocrinology Branch of the NIMH to provide informatics support to the P.O.W.E.R. Study, once of the most active protocols at the NIH Clinical Center,”   noted Frank Pierce, CEO and President of Esprit Health.  “By selecting eSphere for their system, the NIMH will be giving its study team a set of tools that will help analyze their clinical trial data, and ultimately produce better outcomes.”

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

Esprit Health Announces New Specimen Tracking Module

CHICAGO, ILL., March 4, 2005Esprit Health, LLC a privately held company that specializes in information technology for automating the clinical research process, today announced the general availability of its newest addition to the suite of solutions for eSphere, its industry leading clinical research data management system for healthcare.

"For researchers and laboratories, the process for the storage and periodic retrieval of research specimens is an incredibly time consuming," said Donald Dorfman, Vice President of Esprit Health. "The collection of specimen samples in a research study as well as for future research needs release of eSphere continues to revolutionize the way informatics technology supports clinical researchers requires that they be correctly identified, cataloged, stored under proper conditions and be easily retrived when needed. The eShere Specimen Tracking module provides the ability to easily perform these functions which are critically important to research."

The Specimen Tracking System can be implemented as a standalone system to catalog specimens, track their location and retrieve them as needed or as part of eSphere, a complete research data management system. The eSphere system includes a comprehensive demographic database that can be used with as much detailed data as needed. Subject data and cohort assignments are integrated with protocol events and data as well as the specimen information.

Features of the Specimen Tracking system include:

·         Easy to setup, understand and use

·         Subject query and identification with extensive database of demographic data

·         Catalog specimen receipt manually or bar code scan

·         Automatic link of specimen and specimen type to subject

·         User defined rules assist data entry and improve accuracy

·         Automatic assignment to storage locations –floors/room and refrigerator, shelf, box and position in the box

·         Tracking of refrigerator and box capacity and automatic assignment to new box

·         Visual map of box contents with icons reflecting specimen type

·         Single repository for all samples avoids duplication of assignment location

·         Quick and accurate data entry tracks descriptors and all identification numbers

·         Audit trail maintains complete specimen history (when received, entered into system, aliquoted, and delivered).

·         Status of all specimens (e.g. quantity left, number of times retrieved, reason for retrieval) available at any time

·         Powerful search engine with customizable parameters is easy to use and produces results immediately

Pricing and Availability

eSphere SPEcimen Tracking System is available now. Contact Esprit Health at 312-787-6412 for pricing, as well as information on training, consulting and technical support.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com.

NHGRI Picks Esprit Health's eSphere for Internet based Survey to Family Physicians

CHICAGO, ILL., August 31, 2004Esprit Health, LLC a privately held company that specializes in technology for automating the clinical research process, announced today that it has signed an agreement with the National Human Genome Research Institute (NHGRI), Bethesda MD, to provide eSphere, a complete clinical research data management system.

  “We are very excited to work with Dr. Colleen McBride, Chief of the Social and Behavioral Research Branch of the NHGRI on this very important project” noted Frank Pierce, CEO and President of Esprit Health. 

Current trends suggest that genetics will become increasingly relevant to and integrated into family medicine.  In recognition of these emerging genomic innovations and their potential for improving primary care practice, the American Academy of Family Physicians (AAFP),in collaboration with the National Human Genome Research Institute (NHGRI)has made genomic medicine the topic of their 2005 Annual Clinical Focus curriculum.   The AAFP is one of the largest medical organizations with a membership that comprises a group of 56,400 active family physicians.  This study seeks to collect data on family physicians’ attitudes and practices related to the genetics of complex disorders.  This information could be useful in understanding and shaping the dissemination of genetic medicine in ways that improve the standard of primary care practice.

In the first phase, a web-based survey will be conducted of members of AAFP.  In the second phase, a sub-sample of those who complete the survey will be re-contacted; half will be members who have enrolled in a year-long web-based curriculum related to medical genetics, and the other half will be those who have chosen not to enroll in the curriculum. 

“By selecting our newest tool, eSphere Online for their Internet based survey of AAFP physicians, the NHGRI will be able to quickly collect and then analyze their survey data, and ultimately produce better outcomes,” said Pierce.

eSphere, the company’s flagship product provides the most advanced, innovative methodology for clinical study management is now integrated with eSphere Online a web-based tool for data collection.  Together they form a complete end-to-end system designed to address 100% of the clinical, research, regulatory and administrative processes and associated costs and provides all of the components necessary for a “true” clinical research data management system.

About Esprit Health

Founded in 1997, with headquarters in Chicago and offices in Tampa, FL, Esprit Health integrates state-of-the-art software, innovative methodologies, healthcare expertise, and implementation know-how to help its customers realize the vision of eSphere – a new model for the healthcare delivery process.

If you would like more information on this topic or Esprit Health go to www.esprithealth.com.  For More Information: Please contact Donald Dorfman, Vice President at 312.787.6412 or dond@esprithealth.com.  Visit Esprit at www.esprithealth.com. Visit Esprit at